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KMID : 0869120140160030219
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기초간호자연과학회지
2014 Volume.16 No. 3 p.219 ~ p.225
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The Effect of Essential Oil on Atopic Dermatitis Model of NC/Nga Mice
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Han Sun-Hee
Seo Young-Mi
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Abstract
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Purpose: This study was aimed to evaluate the effect of blending oils on atopic dermatitis (AD) model of NC/Nga mice.
Methods: Adult NC/Nga mice were assigned to 1 of 3 groups: control group (C, n=8), experimental group [AD-induced group, blending oil-treated group (E=8, 8)]. Mice in the E group were given a treatment of blending oils such as Lavender, Rosemary and Lemon Balm (LRL) for 2 sessions (every day) for 6 days.
Results:The AD-induced mice with LRL blending oils treatment showed a significant decrease in epidermal thickness, number of mast cells and degranulation, expression of TNF-α and scoring of sensual assessment.
Conclusion: LRL blending oils may be a putative resource for the cure of or treatment of AD by the diminution of AD-pathological factors such as the epidermal thickness, the number of mast cells and degranulation as well as the expression of TNF-α.
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KEYWORD
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Atopic dermatitis, Essential oil, Skin
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